Serum Protein Electrophoresis (SPEP) & Immunofixation
Biochemical fraction separation of serum proteins to identify monoclonal immunoglobulin M-protein spikes characteristic of plasma cell dyscrasias.
Clinical Overview & Diagnostic Rationale
SPEP separates serum proteins into albumin, alpha-1, alpha-2, beta, and gamma globulin fractions. Detection of a dense narrow gamma peak (M-spike) confirmed by Immunofixation Electrophoresis (IFE) establishes Multiple Myeloma or MGUS diagnosis.
Primary Indications & Clinical Scenarios
Venous blood sample. Overnight fasting recommended.
Medical Disclaimer: This information is educational and does not replace a consultation with your doctor. Specific diagnostic protocols are individualized following clinical examination at the clinic.
Questions About Your Serum Protein Electrophoresis (SPEP) & Immunofixation?
Want quick answers regarding Serum Protein Electrophoresis (SPEP) & Immunofixation preparation, scan report abbreviations, fasting protocols, or turnaround times? Ask Dr. Narendra Rathore's OncoAssist AI Companion. Trained on patient FAQs, radiation therapy protocols, chemotherapy precautions, and OPD appointment logistics.
Dr. Narendra Rathore
MBBS, MD (Radiotherapy)Professor and Head of Department, Radiation Oncology
RNT Medical College, Udaipur, Udaipur, Rajasthan
Senior Radiation Oncologist with over 15+ years of specialized clinical experience leading high-precision radiation therapy (3D-CRT/IMRT), systemic chemotherapy, and targeted cancer management at RNT Medical College & MB Hospital, Udaipur. Dedicated to evidence-based, compassionate cancer care across Southern Rajasthan.
Schedule Your OPD Consultation
All oncology consultations, scan reviews, and treatment planning with Dr. Narendra Rathore are conducted strictly in-person at MB Hospital campus, Udaipur.
- Original Biopsy & Histopathology Reports
- CT / MRI / PET Scan Films & DICOM CDs
- Prior Doctor Prescriptions & Chemotherapy Records
- Patient Photo ID & Scheme Card (RGHS / Chiranjeevi)