Research Publications & Clinical Studies

Demonstrates the clinical safety and speed of conscious sedation protocols over general anaesthesia in delivering HDR intracavitary brachytherapy for cervical cancer patients in western Rajasthan.

Quantifies 3D inter-fraction setup errors and safety margins using EPID technology during conformal 3D-CRT in head and neck cancer patients.

Evaluates the sensitivity of dose distribution to applicator reconstruction errors and its impact on Organs-at-Risk (rectum, bladder) during HDR brachytherapy planning.

Compares clinical efficacy, toxicities, and local response of weekly Paclitaxel vs. Cisplatin schedules combined with external radiation in locally advanced carcinoma cervix.

Presents institutional outcomes of 3-weekly high-dose Cisplatin versus weekly Cisplatin regimens during concurrent radiotherapy in head and neck malignancies in Southern Rajasthan.

Analyzes volumetric dose-volume histograms (DVH) for D2cc rectum and bladder doses across different applicator positions in cervical cancer HDR brachytherapy.

Validates 3D volumetric gamma analysis against traditional 2D planar fluence measurements for patient-specific IMRT and VMAT plan verification.

Compares 7 Gy x 3 fractions vs. 9 Gy x 2 fractions in Cobalt-60 HDR intracavitary brachytherapy for cervical cancer stages IIB-IIIC1, assessing local control and late rectal toxicity.

Proves physical and dosimetric equivalency between Cobalt-60 and Iridium-192 sources in HDR cervical brachytherapy, establishing Co-60 as a cost-effective option for resource-restricted setups.

Investigates step size optimization (2.5 mm vs. 5 mm) for Co-60 source stepping in intraluminal brachytherapy treatment for esophageal and bronchial tumors.

Presents a rare clinical case of solitary bone plasmacytoma evolving into full POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal protein, Skin changes).

Compares tolerance, nutritional compliance, and response rates between concurrent vs sequential chemoradiation in elderly esophageal carcinoma patients suffering from severe dysphagia.

Long-term institutional experience establishing Co-60 miniaturized HDR sources as an economical, highly sustainable alternative to Ir-192 in public sector cancer centers across western India.

Demonstrates that conscious sedation yields non-inferior geometry and dose coverage to HR-CTV compared with general anaesthesia in cervical intracavitary brachytherapy.

Analyzes clinical management strategies, renal decompression requirement, and tolerance in stage IIIB cervical cancer patients presenting with obstructive uropathy and elevated blood urea.

Detailed institutional study measuring bladder and rectal dose variations between patients undergoing applicator insertion under IV conscious sedation vs general anaesthesia.

Reports a rare histopathological transformation of a low-grade brain astrocytoma into a secondary CNS primitive neuroectodermal tumor (PNET) following radiation therapy.

Comparative treatment planning study analyzing step size impact on dose homogeneity and mucosal hotline doses in intraluminal Co-60 and Ir-192 brachytherapy.

Early pioneering review on the immunomodulatory mechanisms, natural killer cell activation, and antioxidant protective effects of Spirulina during cancer chemotherapy.

Investigates serum C-reactive protein (CRP) and acute phase reactants as predictive biomarkers for severe grade 3/4 oral mucositis during chemoradiotherapy for head & neck cancer.